![]() Sonohysterography with infusion of saline solution, in particular with 3-dimensional technology, may be a reasonable alternative to diagnostic hysteroscopy, although relatively few well-designed trials have addressed this issue. Hysterosalpingography and baseline transvaginal ultrasonography are insufficiently sensitive alternatives. One large series has reported a 22.9% incidence of endometrial cavitary abnormalities diagnosed at pre-cycle office hysteroscopy in this patient group. The incidence of cavitary abnormalities in this population varies. The value of performing this procedure before an initial cycle in patients without previous implantation failure has not been definitively confirmed in prospective randomized trials, but would seem logical in an effort to minimize the number of cycles a patient must undergo. Published trials have demonstrated a relatively high incidence of cavitary abnormalities diagnosed at outpatient hysteroscopy in patients with previous IVF-ET cycle failure, the correction of which markedly improves outcomes. The role of routine uterine cavity evaluation before an in vitro fertilization–embryo transfer (IVF-ET) cycle has not been uniformly accepted. It is a simple, safe, quick, and inexpensive technique with minimal complications. (10) found SIS to be more accurate than hysterosalpingography and in complete agreement with hysteroscopy. Saline infusion sonography has become an integral part of the first-line screening tests for patients undergoing IVF and has been demonstrated to be as reliable as hysteroscopy in the detection of endometrial polyps and submucosal myoma (2). All of these patients were asymptomatic at Discussion The positive findings on SIS included uterine septum (9.0%), endometrial polyp (45.4%), intramural fibroid, 1 cm in size, with normal endometrial cavity (9.0%), cystic endometrial changes with negative Doppler findings (9.0%), cervical stenosis (18.1%), and calcification in superior aspect of uterine cavity with no distortion of cavity (9.0%). Eleven of 36 patients (30.5%) had positive findings on SIS. The mean age of the patients was 34.2 ± 4.7 years. The SIS was performed in 36/59 patients Results After obtaining Institutional Review Board (IRB) approval, the patients undergoing FET cycles, who had consented for review of their medical records, were included in the study and their medical records were screened for SIS findings.įifty-nine patients underwent FET between September 2005 and June 2006, using their own or donor embryos. This study was a retrospective cohort analysis conducted at the division of Reproductive Endocrinology and Infertility.
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